Loss of the translational repressor 4E-BP1 promotes skin carcinogenesis
Loss of 4E-BP1 increased papilloma burden, keratinocyte proliferation, and tumour vascularisation in a mouse model of skin carcinogenesis.
01 / Profile
Researcher & open-source developer
Yibin Zhou
I investigate how cellular states and spatial context shape tissue biology. I also build reproducible tools to make complex data easier to study.
AffiliationFudan University
LocationShanghai, China
Focus
Skin biology · cancer immunology · disease mechanisms
Methods
Single-cell · multi-omics · machine learning
Practice
R · Python · reproducible research
02 / Research
Biology in context.
- 01
Cellular states
How do cellular states emerge, persist, and change in healthy and diseased skin?
- 02
Cancer immunology
How do tumour and immune cells reshape one another across space and time?
- 03
Disease transitions
Which molecular programmes connect tissue organisation with disease progression?
03 / Publications
Publications
2026
2025
Clinical Characteristics, Pathogen Distribution, and Factors Affecting Visual Outcomes of Pediatric Post-Traumatic Endophthalmitis
A clinical study of paediatric post-traumatic endophthalmitis examining patient characteristics, pathogen distribution, and factors associated with visual outcomes.
04 / Projects